Dott. Gian Paolo Caviglia
- f502-c001 Dottorato in Fisiopatologia Medica
- Dottorato: 28° ciclo
- Matricola: 314908
Contatti
- 116333922
- 116333976
- caviglia.giampi@libero.it
- Dipartimento di Scienze Mediche, Laboratorio di Fisiopatologia Epatica e Digestiva, Via San Massimo 24, Torino
- https://dott-fisiopatologia.campusnet.unito.it/do/studenti.pl/Show?314908
- VCard contatti
- QRcode contatti
Supervisore
Antonina SmedileTesi di dottorato
Serum micro-RNA profiling in chronic hepatitis B virus infected patients with hepatocellular carcinoma
Attività di ricerca
Caviglia GP. I microRNA nell'epatite virale. ReAd Files. 2015; 16(3): 26-7. Comment.
Caviglia GP, Touscoz GA, Pellicano R, Astegiano M. Fecal calprotectin: a biomarker for intestinal inflammation. Inflamm Cell Signal. 2015; 2: e563. Research Highlight.
Caviglia G, Rosso C, Fagoonee S, Cisarò F, Andrealli A, Smedile A, Pellicano R. Endocrine manifestations of chronic HCV infection. Minerva Endocrinol. 2015; 40(4): 321-9. Review.
Ribaldone DG, Fagoonee S, Astegiano M, DeAngelis C, Smedile A, Caviglia GP, Petrini E, Greco A, Pellicano R. Coxib's safety in patients with inflammatory bowel disease: a meta-analysis. Pain Physician. 2015; 18(6): 599-607. Meta-analysis.
Caviglia GP. L-arginine, apoptosis and gastric cancer: any role for Helicobacter pylori? Panminerva Med. 2015; in press. Letter.
Caviglia GP, Pellicano R. On "Diagnostic value of aberrant gene methylation in stool sample for colorectal cancer or adenomas: a meta-analysis". Panminerva Med. 2015; in press. Letter.
Rosso C, Mezzabotta L, Gaggini M, Salomone F, Gambino R, Marengo A, Saba F, Vanni E, Jouness RI, Saponaro C, Buzzigoli E, Caviglia GP, Abate ML, Smedile A, Rizzetto M, Cassader M, Gastaldelli A, Bugianesi E. Peripheral insulin resistance predicts liver damage in non-diabetic subjects with non-alcoholic fatty liver disease. Hepatology. 2015; In press. Original Article.
Rosso C*, Caviglia GP*, Abate ML, Vanni E, Mezzabotta L, Touscoz GA, Olivero A, Marengo A, Rizzetto M, Bugianesi E, Smedile A. Cytokeratin 18-Aspartate396 apoptotic fragment for fibrosis detection in patients with non-alcoholic fatty liver disease and chronic viral hepatitis. Dig Liver Dis. 2015; In press. *These authors equally contributed to the manuscript. Original Article.
Caviglia GP. Riduzione dell'espressione di micrRNA 122 nei portatori CT/CC IFNL3 e durante la progressione della fibrosi in pazienti con epatite cronica C. ReAd Files. 2015; 16(1): 26-7. Comment.
Caviglia GP, Pellicano R. Serum cytokeratin-18 levels for liver fibrosis prediction. Hepat Mon. 2015; 15(8): e30853. Letter.
Caviglia GP*, Abate ML*, Petrini E, Gaia S, Rizzetto M, Smedile A. Highly sensitive apha-fetoprotein, Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein and des-gamma-carboxyprothrombin for hepatocellular carcinoma detection. Hepatol Res. 2015; In press. These authors equally contributed. Original Article.
Caviglia GP, Abate ML, Pellicano R, Smedile A. Chronic hepatitis B therapy: available drugs and treatment guidelines. Minerva Gastroenterol Dietol. 2015: 61(2): 61-70. Review.
Caviglia GP, Fagoonee S, Pellicano R.Re: El-Garem et al.: Seminal Helicobacter pylori treatment improves sperm motility in infertile asthenozoospermic men (Urology 2014:84:1347-1350). Urology. 2015; 85(5): 1217. Letter.
Caviglia GP, Pellicano R, Astegiano M. Reply to: Diagnostic power of fecal calprotectin in inflammatory and functional intestinal disorders. Scand J Gastroenterol. 2015; 50(5): 623-4. Letter.
Petrini E, Caviglia GP, Abate ML, Fagoonee S, Smedile A, Pellicano R. MicroRNAs in HBV-related hepatocellular carcinoma: functions and potential clinical applications. Panminerva Med. 2015. In press. Review.
Greco A*, Caviglia GP*, Brignolo P, Ribaldone DG, Reggiani S, Sguazzini C, Smedile A, Pellicano R, Resegotti A, Astegiano M, Bresso F. Glucose breath test and Crohn's disease: Diagnosis of small intestinal bacterial overgrowth and evaluation of therapeutic response. Scand J Gastroenterol. 2015; 50(11): 1376-81. *These authors equally contributed. Original Article.
2014
Caviglia GP, Sciacca C, Smedile A. Chronic HCV infection and lymphoproliferative disorders: association or causal relationship? Abdomen. 2014; 1(1): e4551. Research Highlight.
Caviglia GP, Pantaleoni S, Touscoz GA, Adriani A, Rosso C, Smedile A, Pellicano R, Astegiano M, Bresso F. Fecal calprotectin is an effective diagnostic toolthat differentiates inflammatory from functional intestinal disorders. Scand J Gastroenterol. 2014; 49(12): 1419-24. Original Article.
Caviglia GP, Sciacca C, Abate ML, Olivero A, Rosso C, Touscoz GA, Ciancio A, Rizzetto M, Smedile A. Chronic HCV infection and lymphoproliferative disorders: mixed cryoglobulinemia syndrome, MGUS and B-cell non-Hodgkin lymphoma. J Gastroenterol Hepatol. 2015; 30(4): 742-7. Original Article.
Rosso C, Abate ML, Ciancio A, Strona S, Caviglia GP, Olivero A, Touscoz GA, Rizzetto M, Pellicano R, Smedile A. IL28B polymorphism genotyping as a predictor of rapid virologic response during interferon plus ribavirin treatmnent in hepatitis C virus genotype 1 patients. World J Gastroenterol. 2014; 20(36): 13146-52. Original Article.
Tandoi F*, Caviglia GP*, Pittaluga F, Abate ML, Smedile A, Romagnoli R, Salizzoni M. Prediction of Occult hepatitis B virus infection in liver transplant donors through hepatitis B virus blood markers. Dig Liv Dis. 2014; 46(11): 1020-4. *These authors equally contributed. Original Article.
De Nicolò A, Boglione L, Ciancio A, Cusato J, Strona S, Cardellino CS, Abdi AM, Cariti G, Troshina G, Caviglia GP, Smedile A, Rizzetto M, Di Perri G, D'Avolio A. Telaprevir-S isomer enhances ribavirin exposure and the ribavirin-related haemolytic anaemia in a concentration-dependent manner. Antiviral Res. 2014; 109: 7-14. Original Article.
Burdino E, Ruggiero T, Proietti A, Milia MG, Olivero A, Caviglia GP, Marietti M, Rizzetto M, Smedile A, Ghisetti V. Quantification of hepatitis B surface antigen with the novel DiaSorin LIAISON XL Murex HBsAg Quant: correlation with ARCHITECT quantitative assays. J Clin Virol. 2014; 60(4): 341-6. Original Article.
Caviglia GP, Touscoz GA, Smedile A, Pellicano R. Noninvasive assessment of liver fibrosis: key messages for clinicians. Pol Arch Med Wew. 2014; 124(6): 329-35. Review.
2013
Smedile A, Abate ML, Caviglia GP. Standard therapy for chronic hepatitis B. Floreani A. Chronic hepatitis B and C, Ed. Minerva Medica, 2013. Book Chapter.
Caviglia GP, Ciancio A, Rosso C, Abate ML, Olivero A, Pellicano R, Touscoz GA, Smedile A, Rizzetto M. Non-invasive methods for the assessment of hepatic fibrosis: transient elastography, hyaluronic acid, 13C-aminopyrine breath test and cytokeratin 18 fragment. Ann Hepatol. 2013; 13(1): 91-7. Original Article.
D'Avolio A, De Nicolò A, Cusato J, Ciancio A, Boglione L, Strone S, Cariti G, Troshina G, Caviglia GP, Smedile A, Rizzetto M, Di Perri G. association of ITPA polymorphism rs6051702/rs1127354 instead of rs7270101/rs1127354 as predictor of ribavirin-associated anemia in chronic hepatitis C treated patients. Antiviral Res. 2013; 100(1): 114-9. Original Article.
Petta S, Rosso C, Leung R, Abate ML, Booth D, Salomone F, Gambino R, Rizzetto M, Caviglia P, Smedile A, Grimaudo S, Cammà C, Craxì A, George J, Bugianesi E. Effect of IL28B rs12979860 CC genotype on metabolic profile and sustained virologic response in patients with genotype 1 chronic hepatitis C. Clin Gastroenterol Hepatol. 2013; 11(3): 311-7. Original Article.
Caviglia GP, Tandoi F, Abate ML, Ciancio A, Romagnoli R, Smedile A. HBV cccDNA evaluation in HBV-core antibody (HBcAb)-positive liver donors. Hepatology 2015; 62S: 1056-7.
Tandoi F, Caviglia GP, Olivero A, Martini S, Lupo F, Ottobrelli A, Smedile A, Romagnoli R, Rizzetto M, Salizzoni M. Esperienza monocentrica di trapianto di fegato per epatopatia HBV-HDV correlata. XXXIX Congresso Nazionale Società Italiana Trapianti d'Organo, L'Aquila 24-26 Settembre 2015.
Caviglia GP, Olivero A, Smedile A. Aggiornamenti sulla terapia dell'epatite B e Delta. XI Convegno Nazionale Aggiornamenti in Epatologia e Gastroenterologia, Verona 6-7 Ottobre 2015.
Tandoi F, Caviglia GP, Olivero A, Martini S, Lupo F, Ottobrelli A, Smedile A, Romagnoli R, Rizzetto M, Salizzoni M. Liver transplantation for hepatitis B with delta coinfection: a single center experience. J Viral Hepat 2015; 22S: 110.
Olivero A, Ciancio A, Caviglia G, Strona S, Fontana R, Martini S, Torrani Cerenzia M, NIro G, Smedile A, Rizzetto M. Epidemiology and clinical course of hepatitis delta virus infection over 15 years in a liver center in Northern Italy. J Viral Hepat 2015; 22S:106.
Rosso C, Saponaro C, Mezzabotta L, Vanni E, Gambino R, Saba F, Ibrahim Kamal Jouness R, Gagini M, Buzzigoli E, Caviglia GP, Abate ML, Salomone F, Smedile A, Rizzetto M, Cassader M, Gastaldelli A, Bugianesi E. Deregulation of de novo lipogenesis can be associated with liver damage in patients with non alcoholic fatty liver disease. J Hepatol 2015; 62S:738.
Gaggini M, Saponaro C, Rosso C, Buzzigoli E, Carli F, Ciociaro D, Mezzabotta L, Vanni E, Gambino R, Saba F, Carenzi S, Caviglia GP, Abate ML, Smedile A, Rizzetto M, Cassader M, Bugianesi E, Gastaldelli A. J Hepatol 2015; 62S:509.
Caviglia GP, Abate ML, Petrini E, Gaia S, Manzini P, Carucci P, Rizzetto M, Smedile A. Clinical evaluation of circulating microRNAs as potential biomarkers of hepatocellular carcinoma in patients with HBV chronic infection. J Hepatol 2015; 62S: 447-8.
Abate ML, Caviglia GP, Petrini E, Gaia S, Carucci P, Smedile A. Highly sensitive α-fetoprotein, Lens culinaris agglutinin reactive fraction of α-fetoprotein and des-γ-carboxy prothrombin for hepatocellular carcinoma detection in an Italian cohort. J Hepatol 2015; 62S: 441-2.
Greco A, Caviglia GP, Ribaldone DG, Brignolo P, Reggiani S, Sguazzini C, Smedile A, Pellicano R, Resegotti A, Astegiano M. Glucose breath test and Crohn's disease: diagnosis of small intestinal bacterial overgrowth and evaluation of therapeutic response. Dig Liver Dis 2015; 47S: e177.
Rosso C, Saponaro C, Mezzabotta L, Vanni E, Gambino R, Saba F, Ibrahim Kamal Jouness R, Gaggini M, Buzzigoli E, Caviglia GP, Abate ML, Salomone F, Smedile A, Rizzetto M, Cassader M, Gastaldelli A, Bugianesi E. Liver damage can be associated with deregulation of de novo lipogenesis pathway in subjects with non alcoholic fatty liver disease. Dig Liver Dis 2015; 47S: e5.
Caviglia GP, Abate ML, Petrini E, Gaia S, Manzini P, Carucci C, Rizzetto M, Smedile A. Clinical evaluation of circulating microRNAs as potential biomarkers of hepatocellular carcinoma in patients with chronic HBV infection. Dig Liver Dis 2015; 47S: e47.
2014
Smedile A, Caviglia GP. Epatite B: diagnosi, terapia e follow-up dell'epatite cronica HBV. X Convegno Nazionale Aggiornamenti in Epatologia e Gastroenterologia, Verona27-28 Ottobre 2014.
Vanni E, Rosso C, Mezzabotta L, Saponaro C, Gaggini M, Gambino R, Ibrahim KJ, Saba F, Buzzigoli F, Carli F, Caviglia GP, Abate ML, Smedile A, Rizzetto M, Cassader M, Gastaldelli A, Bugianesi E. Metabolic analysis identifies new biomarkers of liver damage in NAFLD. Hepatology. 2014; 60(S1): 227A.
Rosso C, Vanni E, Mezzabotta L, Gambino R, Saba F, Salomone F, Ibrahim KJ, Gaggini M, Buzzigoli E, Saponaro C, Carli F, Caviglia GP, Abate ML, Smedile A, Rizzetto M, Cassader M, Gastaldelli A, Bugianesi E. Validation of surrogate indexes of peripheral and hepatic insulin restance and evaluation of their utility as non-invasive predictors of histological features in patients with non-alcoholic fatty liver disease. Hepatology. 2014; 60(S1): 589A.
Mezzabotta L, Rosso C, Vanni E, Gambino R, Ibrahim KJ, Saba F, Salomone F, Gaggini M, Buzzigoli E, Saponaro C, Carli F, Caviglia GP, Abate ML, Smedile A, Rizzetto M, Cassader M, Gastaldelli A, Bugianesi E. Oxidative stress-inducible factors promote liver fibrosis in patients with non-alcoholic fatty liver disease. Hepatology. 2014; 60(S1): 615A.
Tandoi F, Caviglia GP, Pittaluga F, Abate ML, Smedile A, Romagnoli R, Salizzoni M. Predizione dell'infezione occulta da virus dell'epatite B nei donatori di fegato prima del trapianto. XXXVIII Congresso S.I.T.O. Siena 24-26 Settembre 2014. C17.3.
De Nicolò A, Ciancio A, Boglione L, Mohamed Abdi A, Smedile A, Caviglia GP, Di Perri G, Rizzetto M, D'Avolio A. A concentration-dependent pharmacokinetic interaction with telaprevir increases ribavirin concentrations and leads to higher haemoglobin drop. J Hepatol. 2014; 60(S1): S 482.
Saponaro C, Vanni E, Gaggini M, Rosso C, Mezzabotta L, Gambino R, Buzzigoli E, Carli F, Abate ML, Saba F, Salomone F, Caviglia GP, Smedile A, Rizzetto M, Cassader M, Bugianesi, Gastaldelli A. Quantitative and qualitative analysis of plasma free fatty acids and their impact on liver damage in NAFLD patients. J Hepatol. 2014; 60(S1): S354.
Rosso C, Vanni E, Mezzabotta L, Gambino R, Saba F, Carenzi S, Gastaldelli A, Gaggini M, Buzzigoli E, Saponaro C, Carli F, Caviglia GP, Abate ML, Salomone F, Smedile A, Rizzetto M, Cassader M, Bugianesi E. Impact of fat versus glucose load on oxidative stress in non-alcoholic fatty liver disease. J Hepatol. 2014; 60(S1): S353.
Mezzabotta L, Vanni E, Rosso C, Gaggini M, Gambino R, Buzzigoli M, Saponaro C, Ciociaro D, Abate ML, Saba F, Salomone F, Caviglia GP, Carenzi S, Smedile A, Rizzetto M, Cassader M, Gastaldelli A, Bugianesi E. J Hepatol. 2014; 60(S1): S352.
Vanni E, Mezzabotta L, Rosso C, Gaggini M, Gambino R, Salomone F, Buzzigoli E, Saponaro C, Saba F, Ciociaro D, Caviglia GP, Abate ML, Carenzi S, Smedile A, Rizzetto M, Cassader M, Gastaldelli A, Bugianesi E. Alteration in glucose metabolism after an oral glucose load and relationship with liver damage in patients with NAFLD. J Hepatol. 2014; 60(S1): S352-3.
De Nicolò A, Ciancio A, Boglione L, Mohamed Abdi A, Smedile A, Caviglia GP, Di Perri G, Rizzetto M, D'Avolio A. The co-administration of telaprevir increases ribavirin plasma and intra-erythrocytic concentrations, causing higher onset of anemia. Dig Liv Dis. 2014; 46(S1): e10.
Mezzabotta L, Vanni E, Rosso C, Gaggini M, Gambino R, Buzzigoli E, Saponaro C, Ciociaro D, Abate ML, Saba F, Salomone F, Caviglia GP, Carenzi S, Smedile A, Rizzetto M, Cassader M, Gastaldelli A, Bugianesi E. Alteration in lipid metabolism after an oral fat load in non-alcoholic fatty liver disease. Dig Liv Dis. 2014; 46(S1): e53.
Rosso C, Vanni E, Mezzabotta L, Gambino R, Saba F, Carenzi S, Gastaldelli A, Gaggini M, Buzzigoli E, Saponaro C, Carli F, Caviglia GP, Abate ML, Salamone F, Smedile A, Rizzetto M, Cassader M, Bugianesi E. effects of glucose and fat load on oxidative stress in patients with non-alcoholic fatty liver disease. Dig Liv Dis. 2014; 46(S1): e54.
Vanni E, Mezzabotta L, Rosso C, Gaggini M, Gambino R, Salomone F, Buzzigoli E, Saponaro C, Saba F, Ciociaro D, Caviglia GP, Abate ML, Carenzi S, Smedile A, Rizzetto M, Cassader M, Gastaldelli A, Bugianesi E. Alteration in glucose metabolism after an oral glucose load in patients with non-alcoholic fatty liver disease. Dig Liv Dis. 2014; 46(S1): e54.
2013
Caviglia GP, Tandoi F, Abate ML, Pittaluga F, Touscoz GA, Romagnoli R, Smedile A, and Selizzoni M. Serological characterization of occult HBV infection in the liver donors. Dig Liver Dis, 2013; 45 (S1): S34.
Adriani A, Astegiano M, Canaparo R, Imbalzano E, Riganò D, Caviglia G, Abate ML, Pantaleoni S, Marietti M, Smedile A, and Rizzetto M. Evaluation of TMPT genotype in patients with chronic inflammatory bowel disease (IBD) treated with thiopuryne. Dig Liver Dis, 2013; 45(S2): S99.
Pantaleoni S, Touscoz GA, Caviglia GP, Adriani A, Sguazzini C, Sapone N, Reggiani S, Rizzetto M, and Astegiano M. Fecal calprotectin is an effective diagnostic tool that differentiates pathological from functional intestinal disorders. Dig Liver Dis, 2013; 45(S2): S104.
Adriani A, Pantaleoni S, Canaparo R, Imbalzano E, Riganò D, Caviglia GP, Smedile A, Ribaldone DG, Sapone N, Pellicano R, and Astegiano M. Inosine triphosphate pyrophosphatase 94 C>A polymorphism in inflammatory bowel disease (IBD) patients treated with thiopurine. Dig Liver Dis, 2013; 35(S2): S108.
Rosso C, Vanni E, Mezzabotta L, Gambino R, Carenzi S, Saba F, Buzzigoli E, Gaggini M, Caviglia GP, Cassader M, Smedile A, Rizzetto M, Gastaldelli A, and Biugianesi E. Metabolic alterations of lipid kinetics in NAFLD patients and their contribution to liver damage. J Hepatol, 2013; 58(S1): S549.
Rosso C, Petta S, Abate ML, Vanni E, Mezzabotta L, Gramaudo S, Caviglia GP, Gambino R, Cassader M, Rizzetto M, Smedile A, and Bugianesi E. PNPLA3 gene variants and insulin resistance in patients with genotype-1 chronic hepatitis C. Hepatology, 2013; 58(S4): 1181A-1182A.
The Global Viral Hepatitis Summit, Berlino, Germania, 26-28 Giugno 2015
The International Liver Congress - EASL 2015, Vienna, Austria, 22-26 Aprile 2015
Frontiers in regenerative medicine, Torino, Via Nizza 52, 19-20/02/2015
2014
Insufficienza epatica acuta: prospettive terapeutiche attuali e future. Torino, 23 Ottobre 2014
Nuove prospettive nel trattamento dei difetti del ciclo dell'urea ad esordio acuto neonatale. Terapia tradizionale, terapia cellulare epatica, trapianto di fegato. Torino, 08 Maggio 2013
47° riunione generale annuale A.I.S.F., Università di Roma "Sapienza", Roma, 20-21 Febbraio 2014
2013
46a riunione generale annuale A.I.S.F., Università di Roma "Sapienza", Roma, 23-24 Febbraio 2013
5° corso Patologie Rare in Gastroenterologia. San Giovanni Antica Sede,06/05/2015, 10/06/2015, 30/09/2015, 28/10/2015, 25/11/2015
Il trasferimento di conoscenze in Ateneo: dalla ricerca alla valorizzazionedell'innovazione, 3-02-2015 Campus Luigi Einaudi
Preferential exome sequencing in malattie genetiche. MBC - HuGef. 13/01/2015
2014
4° corso Patologie Rare in Gastroenterologia. San Giovanni Antica Sede, 07/05/2014, 04/06/2014, 24/09/2014, 29/10/2014, 19/11/2014
Dall'epatite alla cirrosi HBV correlata: aspetti pratici clinico-terapeutici per il medico specialista. San Giovanni Antica Sede. 11/06/2014 - 12/06/2014
Molecular epidemiologic studies of colorectal cancer. MBC - HuGeF. 06/06/2014
microRNA in biofluids and exosomes. Exiqon webinar. 14/05/2014
Genomics, integromics and precision medicine: applications to colorectal cancer. MBC - HuGeF. 13/05/2014
Efficient extraction of NGS-quality RNA and DNA from FFPE tissues. A novel method of active paraffin removal. Covaris webinar. 17/04/2014
2013
Patologie rare in garstroenterologia. San Giovanni Antica Sede, 06/02/2013, 26/02/2013, 13/03/2013, 17/04/2013
Progetto VenerBì-2: hot topics nel trattamento dell'epatite B. Art Hotel Olimpic, Torino, 25/10/2013
Regolamento Open Access di Ateneo: le logiche, i diritti, la pratica. Aula Magna Università di Torino, 04/10/2013
Workshop sui grant dello European research Council. Aula Magna Campus Cle, 18/09/2013
Seminari Scientifici del Dipartimento di Scienze Mediche. 18/09/2013 e 09/10/2013
Laboratorio di scrittura progetti "Towards Horizon 2020". Aula Magna Campus Cle. 01/07/2013
Circulating biomarkers as tool for early diagnostics. Bioindustry Park, 21/06/2013
Dall'epatite alla cirrosi HBV correlata: aspetti pratico-terapeutici per il medico specialista. San Giovanni Antica Sede, 15-16 Maggio 2013
Where do MHC class II-bound peptides come from?implications for immunity to viruses, self and cancer. Laurence C. Eisenlohr, MBC, 06/05/2013
D-day 2015, 16/09/2015
2013
Corso di inglese scientifico, dal 20/09/2013 al 17/12/2013, 4 ore settimanali
Introduzione alla ricerca bibliografica, 16/09/2013, 17/09/2013
Corso di Biostatistica, 13/06/2013, 18/06/2013, 19/06/2013
D-day 2013, 11/06/2013