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  • Dottorato: 34° ciclo
  • Matricola: 751740

Tesi di dottorato

Recent studies highlight that mesenchymal stem cell–derived EVs (MSC-EVs) play a role in modulating ER stress-induced pathologies. In our work we evaluated the regulation of different ER-Stress related genes in a serum deprivation model of HCECs treated with MSC-EVs and Serum- derived extracellular vesicles (SER-EV). 

The aim this work is, therefore, to investigate whether EVs, released by human bone marrow MSCs, may be beneficial in reducing ER-stress and HCEC apoptosis induced by an in vitro damage model caused by nutrient-deprivation.

Ultimo aggiornamento: 07/10/2020 12:12
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