Dott.ssa Alice Palermiti

FISIOPATOLOGIA MEDICA
Dottorato: 37° ciclo
Dipartimento di Scienze Mediche
Matricola: 782888
ORCID: orcid.org/0000-0003-0860-280X

Tesi di dottorato

PhD project: Investigation of biomarkers associated with multiple drug intolerance and multiple drug resistance: a pilot study.

The primary endpoint of this project is to identify how patients develop intolerance, trying to clarify their mechanisms and clinical determinants. Then, a pharmacological evaluation and characterization of the types of intolerance has to be performed, considering different biomarkers which can be retrieved in serum or urine. Among these also microbiota-related biomarkers will be considered. Finally, the role of concomitant administration of antidepressant and/or antipsychotic drugs on the onset of drug intolerance will be analyzed.

Attività di ricerca

Training and formation activities:

Partecipation to "Introduzione alla spettrometria di massa clinica" Salerno 9-10 September 2024
Partecipation to "LCMS-dalla regolazione dell’interfaccia all’ottimizzazione della cromatografia" course 27/06/2024
Partecipation"La cromatografia dei composti polari: Pesticidi, Acrilammide Amminoacidi e tanto altro.." course 26/06/24
PhD Lecture: "Summarizing evidence from multiple studies", May 27-28-29, 2024
Partecipation to "TDM e personalizzazione della terapia nell’ambito delle nuove molecole antinfettive e biologiche - Aggiornamento degli ultimi 6 anni" congress 13/03/2024-14/03/2024
"Introduction to Good Laboratory Practice (GLP)" course 05/02/2024
Congress Participation: "19th Residential Course on Clinical Pharmacology of antiretrovirals", 17-18-19 January 2024, Turin
Partecipation to "Il monitoraggio terapeutico del farmaco: perché, come, quando" webinar biomedia 05/12/2023
ICH Good Clinical Practice E6 (R2) Certification on 25/09/2023
E-learning training course FAIR DATA - a.y. 2022-2023 February 2023
E-learning training course OPEN SCIENCE A to Z - a.y. 2022-2023 - February 2023
E-learning training course "Bibliography and bibliometrics like pros. Stay up to date and Develop Literature Syntheses in the Biomedical Domain. 1 June 2022 - 23 September 2022
6th International Mass Spectrometry School in Cagliari, Sardinia for the 17-22 September 2023
Partecipation to (R)Evolution in Infectious Diaseases congress on 3-4 november 2022, Turin
Partecipation to "18th Residential Course on Clinical Pharmacology of Antiretrovirals" 18-20 January 2023
Partecipation to "MASSA2023" Mass Spectrometry 2023 congress Torino, 28-30 june 2023 with the poster titled "Analytical validation of a novel UHPLC-MS/MS method for uridine quantifcation in human and mouse plasma"

Other research activities:

Development and validation of a methodological protocol for pharmacokinetic evaluation of the new Covid-19 Antiviral drugs.
Development and validation of a methodological protocol for quantification of drugs at intracellular level (Remdesivir, Tacrolimus).
Routine analysis of anthypertensive drugs concentrations in patient's different matrices (plasma, urine, saliva).
Routine analysis of antimycotic drugs concentration in plasma.
Routine analysis of cannabinoids galenic products

Pubblicazioni

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